House suspects an emergency room patient has a bigger problem then the E.R. initially diagnosed based on the fact that the patient is too nice. A skeptical House questions the patient’s sunny disposition as the team tries to get to the bottom of his illness, but disagrees with House that niceness is a symptom. Meanwhile, House and Amber are at odds about how much time they each get to spend with Wilson, and Cuddy demands House give his team performance reviews. Guest Cast: Anne Dudek as Amber; Paul Rae as Jeff; Chad Morgan as Deb; Marwan Ghazali as Delivery Man; Chris Emerson as Young Man; Dina Defterios as Luisa Maria; Bobbin Bergstrom as Nurse.