A 600-pound man, George Hagel, is admitted to the hospital after he is found in his apartment in a coma. While they conduct the necessary tests, the team runs into several obstacles due to the sheer mass of the patient, and while sedated and undergoing an MRI, George suddenly awakes in a panic and struggles to get free. Upon awakening, George decides that he is fine and requests a discharge. Afraid that George's problem is bigger than he believes, Cameron takes extreme measures to stop him from leaving. George believes his problems are unrelated to his weight and instructs the team to come up with other theories. Unconvinced by George's reasoning, House discovers the root of his illness during a physical altercation. Meanwhile, House has spent the night in jail after being arrested by Officer Michael Tritter for a number of violations, including resisting arrest. Tritter, putting the squeeze on House, searches his home to find more evidence of his drug abuse and puts House's team on the spot when he questions each of them about House and his relationship with Vicodin, and it becomes evident that House may need to get a lawyer.