Plastic surgeons, best friends and business partners Dr. Sean McNamara (series star Dylan Walsh) and Dr. Christian Troy (series star Julian McMahon) run McNamara/Troy, a prominent South Beach, Florida, practice. A seemingly conservative family man, Sean has come to realize that his financial success can't mask his family problems, including his relationship with his disillusioned wife, Julia (series star Joely Richardson), and troubled son, Matt (series star John Hensley). Likewise, single and promiscuous Christian is discovering that his lucrative career and good looks no longer bring him enough emotional satisfaction, as evidenced by his failed engagement to sexy and confident Kimber Henry (series star Kelly Carlson--not appearing in this episode). Opinionated Dr. Liz Cruz (series star Roma Maffia) serves as the team's anesthesiologist. In the fourth season premiere, Sean and Christian celebrate a milestone surgery and receive an interesting proposition from patient Burt Landau (recurring guest star Larry Hagman), a wealthy medical venture capitalist who wants bigger testicular implants, and his much younger wife, Michelle (recurring guest star Sanaa Lathan). Meanwhile, Julia reveals devastating news about her unborn child to Sean, leaving him full of fear and doubt. Phone sex operator Cindy Plumb (Kathleen Turner) requests that the surgeons make her voice more youthful. And tortured Christian redecorates his apartment after a troubling appointment with his psychiatrist, Dr. Faith Wolper (recurring guest star Brooke Shields).