Jackie is on edge after realizing the stash of pills she stole is quickly dwindling. With a head of steam, Jackie confronts Eddie about his recent text exchanges with Kevin's younger sister, Tunie. Coop remains determined to battle O'Hara for the ER Chief title, but suffers a huge emotional blow. Lou, the down-on-his-luck salesman, returns to the ER much worse for the wear.
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