The team travels into the Atacama Desert, to the old mining town of Humberstone, Chile to investigate why the town was suddenly abandoned overnight.
The team travels to the dense jungles of Belize to investigate a series of paranormal events tied to a 7th century ruthless and cruel Mayan ruler named Lord Smoking Shell.
Terumi's designs for Noel come to fruition and he crows about what he has achieved to Ragna, even as Ragna fights a losing battle against him to save Noel.
Science stands at the brink of unlocking our primal instincts. Advancements in genetic engineering may soon free humans from the limitations that have linked us to the rest of the animal world. Pain, fear, uncertainty and fraily may be things of the past.
The team travels to the United Kingdom to investigate paranormal activity surrounding a historic and elite secret society known as The Hellfire Club.
Kennex and Dorian respond to a suspicious death at a hospital where – before having a fatal cardiac arrest – a man claimed someone was trying to kill him, and inexplicably knew his exact time of death. As the investigation unfolds, a black market for vital organs is uncovered in which bio-mechanical hearts can be resold and remotely "shut off." As the team fights to find the pulse of this 2048 tech-centric crime, Dorian reconnects with a decommissioned DRN.
The chaos on the Alaskan base intensifies as a new Nova threat and a massive army of Maria Lancelot clones descend upon the Photon Generator.
Cedric and his butler are playing a game with no clear winners, and time is running out for Charlotte and Henriette.
While Scott struggles to find his place as an Alpha, he, Allison and Stiles begin to experience strange side effects as a result of reigniting the power within Beacon Hills. They soon discover that the answer to their problems may be found in a new student named Kira, a girl with remarkable powers of her own.
The residents of Storybrooke race to stop Pan from placing another curse on the town.
Freya's wedding day arrives as do gifts from both Killian and Dash. Joanna and Wendy discover the identity of the shifter. When Ingrid discovers some unnerving details about Mike, he takes dangerous measures to complete his plan.
In flashback, we learn about Cyrus’ origin story while Alice seeks out the White Rabbit for answers involving his actions in Wonderland
After a string of delinquent teens go missing, an old Wesen tale of an evil Santa who brings more than just a lump of coal may be the prime suspect. The investigation intensifies as Nick (David Giuntoli) and Hank (Russell Hornsby) take things a little too far. Meanwhile, Monroe (Silas Weir Mitchell) enlists Juliet (Bitsie Tulloch) to surprise Rosalee (Bree Turner) for their first Christmas together with unintended results. Elsewhere, Captain Renard’s (Sasha Roiz) tour of Europe brings him closer to tracking down Adalind (Claire Coffee).
Damon realizes Elena is in danger and enlists Stefan's help to find her. The brothers pay a visit to Aaron (recurring guest star SHAUN SIPOS), and Damon shocks Stefan by revealing his first-hand knowledge of Aaron's family. In an attempt to stop Damon, Dr. Wes (recurring guest star RICK COSNETT) unleashes his secret weapon, forcing Damon to deal with a part of his past he thought was gone forever, as well as the consequences of his decades-long plan for revenge. Meanwhile, Elena is horrified by Dr. Wes' confessions about the dark history of Whitmore College and his own ultimate goal. Finally, a frantic Katherine turns to Matt for help, until she realizes that Nadia (recurring guest star OLGA FONDA) may be the one who can solve her problem.
Oliver is visited by ghosts from the past. After a fight with Cyrus Gold AKA the Acolyte (guest star Graham Shiels), Oliver is drugged and left for dead. Determined to cure him, Felicity makes a risky decision. The cure causes Oliver to hallucinate, and what he sees forces him to confront his past. Meanwhile, Barry continues to help Felicity, and their connection grows stronger. The Arrow asks Lance to look into Gold, but when the stakeout on Gold goes bad, someone is killed. Roy is captured and tortured by Brother Blood (guest star Kevin Alejandro).