After a massive angel slaughter occurs, Sam and Dean arrive at the scene to investigate and are surprised to run into Castiel.
Sheriff Mills calls Sam and Dean for help investigating multiple murders in her small town.
Dean gets a call from an old friend named Sonny asking for help with a ghost that won't leave the home that Dean was sent to when he was younger.
A headline in the local newspaper about some disappearances in the area catches Castiel's (Misha Collins) eye, so he calls Dean (Jensen Ackles) to help him investigate the case.
While investigating two bizarre murders, Sam and Dean realize there is an eyewitness to both gruesome deaths – a German Sheppard.
Sam and Dean discover that the table in the Men of Letters house has an ancient computer attached to it, which they figure they can use to track angels.