The BAU responds quickly after a serial killer releases a new strain of a deadly anthrax virus in Annapolis that threatens the public and puts a member of the team at risk.
Local authorities summon the assistance of the BAU after a series of homicides occur that appear to have been caused by a serial killer's car near Bend, Oregon.
When a serial killer in Buffalo sends a videotape of one of his crimes to the BAU, the team discovers a message from the murderer that begs for help in stopping the killing.
During an investigation of a series of child abductions and murders in Cherry Hill, New Jersey, the BAU concludes the possibility that the last murder may not be the work of the suspect who had been apprehended.
The BAU is called to Texas to investigate a serial killer who is targeting vacationing students on spring break on South Padre Island.
The BAU is summoned to Indiana by local authorities when a serial arsonist threatens the residents of Royal by setting fire to community meeting places that kills many people.
The BAU travels to Boston when the serial killer from one of Agent Hotchner's first cases, which involved one of the most notorious murderers in the history of New England, returns after 10 years.
The BAU investigates a series of deaths involving possible exorcisms in the Washington area that appear to be sanctioned by the Vatican, and SSA Emily Prentiss finds herself personally involved in the case.
The BAU is called to Dallas to investigate when a serial killer lures and kills high-powered executives by posing as a high-class call girl.
The local authorities in Cleveland enlist the help of the BAU to assist in the pursuit of a serial killer who appears to be copying the methods used by famous murderers from the past.
The mother of an abducted child works with the BAU in Seattle to identify a serial killer who kidnaps, murders, and embalms his victims.
The BAU is called to Alabama when young women are being abducted by what appears to be a family working together.
When a young woman in an affluent community in Sarasota, Florida, disappears, the BAU suspects she may have been taken hostage by the partner of a pair of serial killers.
The BAU is called to assist local law enforcement in catching a serial killer, dubbed the "Road Warrior" by the media, who is shooting blonde women as they drive along freeways in Orange County, California.
As a former uniform cop, Morgan takes it personally when a serial killer specifically targets officers on the police force in Phoenix, Arizona.
Emily Prentiss and Jordan Todd go undercover in Atlanta to profile a serial killer who has perfected his skill as a pick-up artist and uses his masculine prowess to lure his next victims.
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