Lynette is angry when Renee starts spending a lot of time with Tom; Bree finds herself falling for Keith; Susan feels guilty about her side job.
Paul Young, now out of prison, returns to Wisteria Lane with an enigmatic new wife; Susan, Mike and M.J. live in an apartment on limited funds; Lynette's successful college friend pays the Scavos an unexpected visit.
Get ready for a showdown... there's a new housewife in town. Vanessa Williams moves to Wisteria Lane - and she's not the only thing shaking things up. The ladies also have to face the return of a sinister "new" neighbor.
Gaby puts herself at risk in an attempt to help Angie; Eddie controls Lynette's fate; Susan faces her financial problems; Bree considers revealing a secret.
Angie turns to Gaby for help when Patrick makes a threat; Bree tries to pay Sam off; Mike and Susan face financial woes.
Angie's ex, Patrick Logan, finally catches up with her; Susan and Gaby plan an elaborate scheme; Lynette sees a different side of Eddie.
The Fairview strangler's past is revealed, including a time when Bree offered him a job and dating advice, when Susan encouraged his interest in art and when Lynette showed him kindness and generosity.
Determined to derail Preston's marriage to Irina, Lynette discovers the truth about her future daughter-in-law; Gaby offers to help Bob and Lee without considering the consequences.
Angie's ex-boyfriend visits Wisteria Lane; Lynette becomes suspicious of Preston's fiance; Katherine comes out of the closet.
Gaby has a chance encounter with supermodels Heidi Klum and Paulina Porizkova in New York; Preston makes a surprising return from Europe; Katherine is confused by her feelings for Robin.
Celia contracts chicken pox; Penny's birthday is forgotten; Bree hires a new employee; Katherine makes a discovery.
Susan causes a stir when she invites Robin into her home; Bree tries to entice Orson; Gaby looks for help with Ana.
Hostility grows between Angie and Gaby; Susan makes friends with a stripper; Tom and Lynette argue about their new therapist; Bree fears Orson might take his own life.
Lynette doesn't like the idea of seeing a couples therapist; Katherine starts seeing a psychiatrist; Angie doesn't approve of Danny's new girlfriend.
Susan turns up the heat for Mike; Bree learns that it will not be easy to undo the hurt she has caused Orson; Lynette discovers Tom's true intentions; Gaby examines feelings she has suppressed about her heritage.
In the aftermath of the plane crash, the residents of Wisteria Lane think about what their lives might have been like had they made different choices.