While the guys take a road trip to a comic book convention in Bakersfield dressed as characters from Star Trek: The Next Generation, Leonard's car is stolen. Meanwhile, the girls stay home and try to appreciate the world of comics.
Sheldon is accused of sexual harassment at the Univesity and winds up dragging Leonard, Raj and Howard into the fray. Southland's REGINA KING guest stars as the University's Director of Employee Relations.
Sheldon unwillingly revisits some Christmas memories during a lively game of Dungeons and Dragons, while Penny, Bernadette and Amy try to find the perfect girl for Raj when he joins the girls for ladies night.
Sheldon plays nursemaid to a sick Amy, while Howard attempts to bond with his father-in-law (guest star CASEY SANDER) on an upcoming fishing trip.
When the girls' trip to Vegas falls through, the guys invite them to play Dungeons & Dragons - causing Sheldon and Amy's relationship to take an unexpected turn. Meanwhile, Raj and Lucy go on a very awkward date.
Howard and Raj try to get to the bottom of why Sheldon disappears every afternoon at 2:45. Meanwhile, Leonard and Penny wrestle with jealousy in their relationship.
Bernadette pressures Howard to move out of his mother's house, while Sheldon finds himself caught in the middle of a fight betweenAmy and Wil Wheaton.
Sheldon's tenuous relationship with renowned scientist STEPHEN HAWKING is threatened by a game of "Words with Friends," while Pennysecretly enrolls in a class at the local college.
The gang celebrates Halloween at Stuart's comic book store. Meanwhile Leonard and Penny discover a new spark in their relationship when he seduces her with science.
When Howard returns from space, he doesn't get the hero's welcome he expected. Meanwhile, Game Night turns into a battle of the sexes.
While the pressures of being in space starts to take its toll on Howard, Amy feels threatened when Sheldon hires a young female assistant, Alex (guest star MARGO HARSHMAN).
When Sheldon learns that Penny is thinking about breaking up with Leonard, he tries to intervene. Meanwhile, Howard is being picked on in space by the other astronauts.
On the sixth season premiere, Howard discovers that he can't escape his mother - even in space! Back on earth, meanwhile, Raj turns his existence as a third wheel into an art form.
When NASA reschedules Howard's mission and puts his wedding plans in jeopardy, he's forced to face his fears and Bernadette's dad (guest star CASEY SANDER).
Howard's wedding plans are in jeopardy after the guys (and Wil Wheaton) throw him a bachelor party. After details of his sexual history are leaked online, Bernadette reconsiders marrying Howard.
When Wolowitz gets tow work with world-renowned scientist STEPHEN HAWKING (guest starring as Himself), Sheldon is willing to do anything to meet his hero.
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