At 548 pounds, a newlywed from Portland, Ore., wants to lose 50 percent of his body weight and live a healthier lifestyle.
Following serious injuries that led to weight gain, a 45-year-old mother tries to slim down and get healthy.
A 543-pound man works to get healthy so he can be a better father and husband; the Harlem Globetrotters host a day of physical challenges.
A 435-pound woman struggles with the hard work and commitment needed to get healthy; Chris helps the woman find closure with her biological father.
Ashley, a cosmetology student from California, tries to lose half of her 323 pounds by her 21st birthday.
Michael, a 28-year-old small-business consultant who weighs 493 pounds, tries to live a healthier lifestyle; Michael's family lends support by pledging to lose 500 pounds.
A 355-pound woman works to lose weight so she can start a family.
Chris helps a man whose struggle with weight has left him jobless and put strain on his relationship.
Chris helps a 445-pound married mother turn her life around.
Chris helps a 30-year-old woman who cares for her 2 young children and sick husband on top of working full time.
Chris tries to help a 26-year-old husband and father, who turned to food at an early age to cope with a difficult childhood.
A young woman works to lose weight and in the process must face the secret that lead to her becoming obese.
Chris helps a 25-year-old former football player who must lose 150 pounds in his first three months in order to stay on track.
A 45-year-old bachelor tries to lose weight and reclaim his life.
A 23-year-old man tries to fulfill a promise he made to his late mother to lose weight and lead a healthier life.
An ambitious 21-year-old woman who weighs nearly 400 pounds embarks on a one-year challenge in hope of losing weight.
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