Brought to the hospital with a tearing aorta, Penny Goldsmith--who has finally met the "love of her life"--worries that fate has played a cruel trick on them both and their future together won't happen. But cardiac surgeon Allan Stewart makes her a promise he feels bound to keep--if he can. Her grown children are not ready to let go of Rita Respass-Brown, but with her kidneys failing and 100,000 people on the transplant waitlist, her chances are not good. Doctors Joseph Del Pizzo and Sandip Kapur will also do everything they can to help. ER doctor Debbie Yi relates to her patient after facing similar heartbreaking disappointment.