Chelsea invites her beautiful college roommate (guest star Tricia Helfer – Battlestar Galactica) to stay at the house while she gets over a bad breakup.
Charlie and Alan wake up together in bed with a strange woman.
Alan recommends that Chelsea get breast reduction surgery and Charlie kicks him out.
Jake refuses to stay with Charlie and Alan after they embarrass him in public.
Alan takes a job working for Evelyn (series star HOLLAND TAYLOR), and Charlie is forced to mend Chelsea and Jake's rocky relationship.
Alan (series star Jon Cryer) plays nursemaid to Judith’s baby and her tipsy mother, Lenore (recurring guest star Annie Potts). Meanwhile, Jake (series star Angus T. Jones) blackmails Charlie with an incriminating photo.
When Charlie’s fiancée, Chelsea, convinces him to let Melissa (recurring guest star Kelly Stables), Alan’s girlfriend, move in, the girls take over the house.
On the seventh season premiere, Charlie (series star Charlie Sheen) must decide between his fiancée, Chelsea (recurring guest star Jennifer Taylor), and his old flame, Mia (recurring guest star Emmanuelle Vaugier). Rock superstar Eddie Van Halen makes a cameo appearance as himself.
For six seasons, Charlie Harper has loved 'em and left 'em. In Season 7, he gets left. TV's #1 comedy pulls a hilarious switcheroo when Charlie's fiancee Chelsea meets a doctor (score one) who's generous, thoughtful and mature (score three more). She vamooses, and Charlie - after pickling himself in booze and self-pity - handles the situation in typical Charlie fashion. Which means lots of laughs for Men fans. But Charlie isn't the only Harper making cement-headed decisions. Alan decides the only thing that separates him from a love god is hair. So he tries the spray-on variety. And Jake decides what he needs to navigate the perilous waters of teenage dating is advice. From Charlie.
On the sixth season finale, Charlie starts to question his relationship with Chelsea when he hears that Mia (guest star Emmanuelle Vaugier) is back in town. Meanwhile, Judith goes into labor and Charlie, Alan and Herb rush her to the hospital.
When Alan and Chelsea become best friends, Charlie decides to take advantage of the situation.
After Charlie reluctantly agrees to let Chelsea move in and he mourns the loss of his bachelor pad, Alan finds that there's not much space left for him in the house. Series star Jon Cryer directs.
Chelsea sets Alan up on a blind date with her new friend? Rose (guest star Melanie Lynskey)!
Evelyn finally meets Chelsea and Charlie then tries to prevent them from becoming friends.
Charlie joins Alan, Herb and his neighbor (Michael Clarke Duncan) in a night of alcohol-fueled sexual reminiscences after Chelsea finds nude pictures of another woman on his phone.
Chelsea gets sick ?and Charlie wants nothing to do with her.