Arizona advises a patient on a potential double amputation.
Couples panic when the hospital announces a nonfraternization policy; Owen and Emma discuss the future; Meredith and Cristina have some girl time; Richard asks the residents for help with a rare cancer case.
The doctors are faced with the consequences of the events at April's wedding; Alex reacts to the news about his father; Callie and Arizona make a decision about their relationship.
Meredith and Cristina bicker about their careers; Bailey talks to Ben about him moving back to Seattle; Shane puts himself in a risky situation; Derek receives a life-changing phone call.
April's visiting sisters get on her nerves; when Matthew and Jackson witness an accident, they must work together; Callie and Arizona work on their relationship.
A sexually transmitted disease affects members of the hospital staff.
Meredith becomes disenchanted with her ignorance of parts of Derek's life.
Derek and Meredith try to be discreet after spending the night together.
Alex works hard to gain the trust of Annie, a patient with a large tumor.
Meredith believes she erred during surgery and endangered her career.
Cristina's encounter with a former nurse changes her forever.
The emergency room fills with patients from the annual bike-messenger race.
Meredith puts her career on the line to save a newborn
Meredith Grey and four other surgical interns try to balance life and work.
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