Uber-mom and control freak Maisy Gibbons returns, and her secret life of being a call-girl intersects with Bree's when she finds out that Rex is cheating on her.
Susan's neurotic and obnoxious mother pays an unannounced visit after she and her boyfriend call it quits.
Lynette goes back to work, leaving Tom in charge of the house.
Lynette tries to put a day-care center in Parcher & Murphy.
Carlos and Gabrielle get temporary custody of Lily; Bree's father and stepmother (Carol Burnett) come to town to mediate; Susan suddenly finds Karl back in her life.
Susan and Ian have their first date; surrogate mother Xaio-Mei gives birth to Gaby and Carlos' baby.
The Wisteria Lane residents have a holiday block party.
Tom feels a new Scavo's Pizzeria employee's interest in Lynette threatens him; Susan considers moving from Wisteria Lane; a neighbor's darkest secret.
Mike worries when Jay wants to enter the workforce.
Michael hires an attractive math tutor.
A young woman clings to life after a brutal attack, leaving the surgical staff optimistic; Meredith puts her career on the line to save a newborn in the hospital nursery.
As Meredith and Cristina discuss their relationship woes at the Emerald City Bar, the bartender collapses.
The Thanksgiving holiday is more difficult for the interns and residents than any of them is willing to admit.
Despite the best efforts of the Seattle Grace staff, the code- black situation escalates.
Finn offers a health update on Doc; Meredith must work with Callie for a day; George works with Derek; Burke and Izzie continue to search for a new heart for Denny.