J.D. is shocked to hear Dr. Cox (who he has called in for a pep talk) tell his interns that eventually, they will screw up and kill a patient. Though upset at first, Dr. Cox's words get to J.D. as well as he fears his first time killing someone will soon be upon him. Elliot is upset with Molly after she disagrees about a patient's promise to attend drug rehab. Carla loses Rowdy and she and the Janitor go looking for him.