Christina's (Cameron Diaz) love life is stuck in neutral. After years of avoiding the hazards of a meaningful relationship, one night while club-hopping with her girlfriends, she meets Peter (Thomas Jane), her perfect match. Fed up with playing games, she finally gets the courage to let her guard down and follow her heart, only to discover that Peter has suddenly left town. Accompanied by Courtney (Christina Applegate), she sets out to capture the one that got away.

The criminal anarchy is hilarious when a foursome of full-time hit men looking to score extra cash kidnap the boss's goddaughter. And when beleaguered wise guy Mel is set up to take the fall, underworld antics and domestic absurdities collide for a working weekend no one will soon forget. Mark Wahlberg, Lou Diamond Phillips, Christina Applegate, Bokeem Woodbine and Antonio Sabato, Jr. star in this explosive action comedy.

The criminal anarchy is hilarious when a foursome of full-time hit men looking to score extra cash kidnap the boss' goddaughter. And when beleaguered wise guy Mel is set up to take the fall, underworld antics and domestic absurdities collide for a working weekend no one will soon forget. Mark Wahlberg, Lou Diamond Phillips, Christina Applegate, Bokeem Woodbine and Antonio Sabato, Jr. star in this explosive action comedy.

The criminal anarchy is hilarious when a foursome of full-time hit men looking to score extra cash kidnap the boss' goddaughter. And when beleaguered wise guy Mel is set up to take the fall, underworld antics and domestic absurdities collide for a working weekend no one will soon forget. Mark Wahlberg, Lou Diamond Phillips, Christina Applegate, Bokeem Woodbine and Antonio Sabato, Jr. star in this explosive action comedy.

Sam thinks that Todd's girlfriend Chloe is lying about her sick aunt in order to prevent Todd from breaking up with her.

Up Close: Christina Applegate

Season 1: Hollywood 411 takes you behind the scenes of SAMANTHA WHO? star Christina Applegate's sexy photoshoot for In Style Magazine!

Christina Applegate has a close encounter with her ex. Plus, Angelina Jolie loses her cool over Jennifer Aniston.

Christina Applegate talks about the encouragement of her "Samantha Who?" cast members, her close friend Lance Bass, and the support that her mom gave her while battling breast cancer.