With the onset of fall and wild snakes hibernating below ground, pastors Andrew Hamblin and Jamie Coots are forced to obtain their deadly, venomous serpents by other means. The men travel to Repticon, a huge snake expo in Columbia, South Carolina, to purchase new snakes for their congregation. Jamie brings newborn rattlesnakes from his church that he will use to trade in for larger snakes at the expo. But Andrew is forced to pawn his prized electric guitar to get money to buy his snakes. The pastors compete head to head at the expo to see who will leave with the most serpents.