When Kuol has a stroke, Andy puts him at the top of the donor list to receive a new heart. However, his transplant is put in jeopardy when the cops threaten to seize the money that was raised for Kuol.
Andy is upset when his rival, an arrogant heart surgeon with no bedside manner, returns to the hospital.
A firefighter must decide whether to be a living donor to her captain, a man who has mistreated her. Meanwhile, Andy's uncle turns up with a stab wound and asks him not to report the incident for fear it will violate his parole.
Andy must decide if he will allow a woman to start a "daisy chain" and donate her kidney to another patient on the chain until an exact match is found for her husband. Meanwhile, Andy suspects that a recent patient is rejecting his new heart.
When a bride is gunned down at her wedding, the team is sent to harvest her lungs to transplant into a college basketball player.
The wife of a billionaire suffers the consequences after a setback leaves her without a new liver and her husband resorts to buying one on the black market. Meanwhile, a friend from Andy's past resurfaces.
Andy treats a car crash victim dying from ALS who asks to be to taken off of life support so his organs can be used to save others. Meanwhile, David tends to a foster parent with pulmonary hypertension who refuses admission to the hospital.
Lisa becomes very attached to an 8-year-old boy who she witnesses being crushed by a ride at a fair. Meanwhile, Andy and David try to get a VAD (ventricular assist device) for one of their patients.
In order to save his life, Andy tries a risky new procedure on his wife's partner, who suffers from an aortic aneurysm.
Following a bus crash, the parents of a football player must make a heartbreaking decision whether to donate his organs. Meanwhile, Andy and Ryan rush to find a procurement team to give a boy a heart transplant he desperately needs.
In order to save his life, Andy tries a risky new procedure on his wife's partner who suffers from an aortic aneurysm.
Andy and the team try to save an 18-year-old college student in need of a double lung transplant but run into a road block that might not allow her to be eligible for a new set of lungs.
After suffering a heart-attack, Andy tells a young pregnant woman that in order to save her and her unborn child she must get a heart transplant. However, unexpected complications with the donor's family place the transplant in jeopardy.
Three Rivers goes inside the emotionally complex lives of organ donors, the recipients. Dr. Andy Yablonski, the highly- skilled workaholic lead organ transplant surgeon, whose good- natured personality and sarcastic wit makes him popular with his patients. His co-workers include Dr. Miranda Foster, a surgical fellow with a rebellious streak; Dr. David Lee, a womanizing surgical resident who's broken as many hearts as he's replaced; and Ryan Abbott, the inexperienced new transplant coordinator.
A new twist on the television medical drama, this one-season series set in a Pittsburgh hospital explores the race-against-time world of organ transplants from the perspective of the medical team, the organ recipients, the donors and their families.
Check out a behind the scenes look at CBS's new medical drama "Three Rivers", starring Alex O'Loughlin.