The Autobots question Optimus's leadership abilities when his decision regarding Megatron proves troublesome.
The quest for the Omega Lock takes the Autobots and the Decepticons to Cyberton for an epic battle.
Starscream proposes a truce to Megatron, but Dreadwing threatens to stand in the way of his return.
When the Decepticons capture him, Smokescreen discovers the final Omega Key and tries to retrieve the other Keys from Megatron himself.
As the race for the Omega Keys grows more desperate, Knock Out harnesses the power of sound, and Starscream uses the power of hyperspeed.
The Autobots learn of the Omega Keys and the incredible secret they hold, while Megatron takes extreme measures to harness the power of the Primes.
Jack teaches Smokescreen about the human world, and Megatron tries to keep Optimus from finding a fabled weapon that could turn the tide of the war.
Silas is given a new lease on life, and he approaches Megatron with a plan to join the Decepticon ranks.
Starscream goes on a quest for Red Energon while a new ally joins Team Prime. But is the new Autobot really what he appears to be?
Arcee is reunited with an old friend, and together they uncover a Decepticon plot engineered by Shockwave.
Miko and Wheeljack embark on a quest for revenge.
The final relic in the hunt may prove more deadly to Bulkhead than the Insecticon warriors who are pursuing him.
During the third relic hunt, the disabling of Soundwave's deployer creates a unique opportunity for Ratchet and Wheeljack.
The second of the relic hunts takes Optimus Prime to the Antarctic, where he gets entangled in shifting alliances between Starscream and Dreadwing.
Team Prime splits up in a race to beat Megatron to the next Iacon relics; the first mission takes Arcee and Bumblebee into New York's subway tunnels.
When a Decepticon warship becomes sentient and directly threatens humanity, the teens discover they are the only ones who can stop it.