Cesare's (Francois Arnaud) diplomatic mission to France is a success: guided through the complexities of the French court by his old advisor Machiavelli (Julian Bleach), Cesare makes an ally of Archbishop d'Amboise, a noble wife - Charlotte d'Albert - as well as a pledge of a military alliance against Milan and the Borgias' enemies. Back in Rome, the seductive and dangerously insane Bianca (Melia Kreiling) takes her own life, prompting Alexander and Cardinal Sforza (Peter Sullivan) to conspire to repay Gonzaga's cruel plot. Lucrezia travels to Naples accompanied by her husband, with Micheletto offering protection. King Ferdinand (Matias Varela) remains steadfast in his determination that little Giovanni will not be recognised at court. Upon learning this, Lucrezia plots against him with a recipe of poisonous mushrooms, but Micheletto will handle the matter on his own.