Pilgrims are flooding to Rome for the Jubilee year celebrations, and the Spear of Longinus is the centerpiece of the show. However Catherina Sforza has a plan to frustrate Alexander's lucrative festival. Across the sea in Kefalonia, the Turkish fleet is destroyed by Mattai's Jewish contacts. Lucrezia senses a change in newly crowned Frederigo, and realizes that she is under constant watch from the royal guard. Cesare and Micheletto discover that Pascal is a spy working for Rufio.