While Alexander worries that Juan has not come home, Savonarola is tortured on the rack but will not confess. Cesare, however, is determined to destroy his legacy as well as his body. Meanwhile, a new suitor for Lucrezia's hand - Alfonso of Aragon - arrives in Rome. Playful Lucrezia sets out to play the minx with him, then surprises herself by falling for him. The Pope's joy, however, is short-lived when he receives dire news, furthered by a shocking confession from Cesare.