Divorced working mother Christine Campbell (series star JULIA LOUIS-DREYFUS) successfully juggles the daily stresses of motherhood and her business. Christine owns a women's 30-minute workout gym with her best friend, Barb (series star WANDA SYKES). Her 10-year-old son, Ritchie (series star TREVOR GAGNON), attends a posh private school, where Christine endures endless encounters with two snooty stay-at-home moms, Marly (series star TRICIA O'KELLEY) and Lindsay (series star ALEX KAPP HORNER). Christine's twentysomething brother, Matthew (series star HAMISH LINKLATER), lives with her and, in a pinch, serves as Ritchie's babysitter. Christine gets along with her charming ex-husband, Richard (series star CLARK GREGG), even better than when they were married, but her life got a lot more complicated after she met Richard's new girlfriend: a nice, young, impossible-to-hate woman also named Christine (series star EMILY RUTHERFURD) -- the new Christine.