Jack and his squad search for a teenage girl, Clare Metcalf (Amber Tamblyn), who disappears from a mental hospital after she suffers an extreme psychotic episode. As the team members investigate Clare's disappearance, they begin to uncover conflicting evidence about her sanity. A hospital worker and her boyfriend think there is nothing wrong with her, but others believe she is extremely ill. The investigators also discover that the apparent suicide of Clare's mother may play a role in Clare's psychological state--and they begin to suspect that her mother's death may not have been self-inflicted after all.
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