Maggie and Meredith team up on a tricky case.
Maggie and Meredith disagree with Derek about the best way to approach a patient's case, which leads to a bigger argument between the couple. Meanwhile, Callie feels responsible when one of her veterans is pushed too far and one doctor's routine procedure results in a devastating diagnosis, on the winter finale.
Secrets of Amelia's past are revealed and Bailey oversees Jo's 1st surgery.
Secrets about Amelia's past addictions come to light and cause problems for her at the hospital; Bailey oversees Jo's first solo surgery; and Arizona must make an executive decision in Dr. Herman's absence. Meanwhile the doctors spring into action when a couple arrives at the emergency room after escaping a fire.
Owen becomes invested with a patient and April's mother pays a visit.
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