After Dean (Jensen Ackles) tells Sam (Jared Padalecki) what their father told him before he died, a distraught Sam sneaks off to Indiana without Dean.

After Dean (Jensen Ackles) tells Sam (Jared Padalecki) what their father told him before he died, a distraught Sam sneaks off to Indiana without Dean. While there, Sam runs into Eva (guest star Katherine Isabelle), a psychic who confesses to Sam she sought him out to warn him of his impending death. Dean discovers Gordon (guest star Sterling K. Brown) is after Sam and races to find his brother in time to save him.

Sam (Jared Padalecki) and Dean (Jensen Ackles) call upon their family friend and fellow hunter Bobby (guest star Jim Beaver) for help after they are stumped by violent and unexplainable happenings on a local college campus. Bobby arrives with a suspicion as to the culprit behind the killing spree and the brothers' escalating feud.

Dean's time is up as he and Sam try to avoid the inevitable...

While Sam and Dean are investigating the disappearance of a man from a tourist location, Dean is shot and killed.

BuddyTV's exclusive interview with Jared Padalecki of Supernatural. http://www.buddytv.com/supernatural.aspx

Jared Padalecki gives us a glimpse into Supernatural Season 3...

Jared talks about the direction of the show...

Supernatural's Jared Padalecki talks about the challenges facing Sam in the upcoming season.

Find out what it's like to play Sam Winchester...