Reese Witherspoon, Jake Gyllenhaal, Meryl Streep, Peter Sarsgaard and Alan Arkin star in Rendition, a thriller from director Gavin Hood (Tsotsi). Witherspoon stars as the American wife of an Egyptian-born chemical engineer who disappears on a flight from South Africa to Washington. The woman desperately tries to track her husband down, while a CIA analyst (Gyllenhaal) at a secret detention facility outside the U.S. is forced to question his assignment as he becomes party to the man s unorthodox interrogation.

Reese Witherspoon, Jake Gyllenhaal, Meryl Streep, Peter Sarsgaard and Alan Arkin star in Rendition, a thriller from director Gavin Hood (Tsotsi).

Reese Witherspoon, Jake Gyllenhaal, Meryl Streep, Peter Sarsgaard and Alan Arkin star in Rendition, a thriller from director Gavin Hood (Tsotsi).

SARAH MICHELLE GELLER, RYAN PHILLIPPE and REESE WITHERSPOON star in this steamy, stylish look at Manhattan's posh youth and their wanton games of sexual manipulation

Bruce Willis and Demi Moore vs. Tom Cruise and Nicole Kidman, Eric and Julia Roberts vs. Donny and Marie Osmond, Bob and Jacob Dylan vs. Jerry and Ben Stiller, Charlie Sheen vs. Emilio Estevez, Mary-Kate Olsen vs. Ashley Olsen, Jennifer Love Hewitt and Scott Wolf vs. Reese Witherspoon and Ryan Phillipe, Joan Rivers vs. Melissa Rivers, Ashley Judd vs. Wynonna Judd, The Baldwin Brothers vs. The Wayans Brothers, Carroll O'Connor vs. Sherman Hemsley, Warren Beaty and Annette Bening vs. Susan Sarandon and Tim Robbins

Reese Witherspoon answers questions about her upbringing in Nashville and her life as an actress.

Strong performances in "Election" and "The Man in the Moon" solidified Reese Witherspoon's place in Hollywood. But it was her star turn in "Legally Blonde" that helped her go from a talented actress to bankable leading lady and A-list star.

As a little girl growing up in Nashville, Reese Witherspoon dreamt of becoming a star and winning an Oscar. After years working as an actress, she landed the role of country music icon June Carter Cash in the film "Walk the Line," which brought her back to her hometown roots. She won the 2006 Academy Award for her performance.

As Avon's Global Ambassador, Reese Witherspoon heads to the UN to discuss issues involving women's rights. She shows everyone how easy it is to make a major difference.

Reese Witherspoon at W Hotel in Westwood