Ted Spaeth's career as a successful architect has caused him to neglect his wife Laura and their six-year old daughter Julie.
Asa McQueen, old prospector, discovers a large sum of money hidden on his mining claim. His resulting spending spree brings him to the attention of both the police and the criminal who hid the money there, the loot from a large-scale robbery.
George Crenshaw has been sentenced to death for the Sunrise Park Murders. On the day his sentence is announced, Molly Weems appears at HP headquarters to state that Crenshaw is innocent, that she can identify the real Sunrise Park killer.
Steve Stankey, a gun-man about thirty, holds up a gas station, and while making his get-away in a taxi, shoots and kills a Highway Patrolman.
A twelve-year-old boy , Jimmy West, runs away from home because of his unreasoning fear of an operation on his eyes. The boy's physician informs Dan that an immediate operation is necessary to preserve Jimmy's sight.
George Mills, business manager for art collector Carter Giles, engineers a plan to "kidnap" some valuable paintings and hold them for "ransom". Plans go awry, forcing Mills and his men to commit murder in order to escape the Highway Patrol's web.
The patrol car of a traffic officer is found abandoned on a country road. Investigation by Dan develops that the officer had been killed by two criminals who were engaged in a stolen car racket.
While on an inspection tour of outlying patrol stations, Dan Mathews is thrown headlong into a terrifying situation - and a race against the clock.
Jim Barnaby, a fugitive gunman, has taken Marge Willis captive for the use of her car.
With inside help, a bandit robs a plant payroll office of $28,000. He makes his escape in a grey sedan.
Seth Roberts, a very unpredictable bank robber was having things pretty much his own way.
A farmer is found dead, badly beaten.
Nailor had served his time for a half a million dollars armored car robbery. The money had never been found.
A duplicate armored truck is used to stage one of the most daring robberies on record. Dan throws all the technical resources of the Highway Patrol into action to track down the truck.
Stan Warren, a smooth, dapper con-man, wanted for murder, speeds toward the desert area in a borrowed car.
A Forest Ranger, patrolling a desolate section of heavy forestland, sees a small plane starting to land about a mile away. He notifies the Highway Patrol that it seems to be trying to make a forced landing.
Highway Patrol starred Broderick Crawford as Chief Dan Matthews, the gruff and dedicated commander of a police force in a large, unidentified Western state, who is always in control and always at the scene of the action.
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